国际眼科纵览

• 综述 • 上一篇    下一篇

影响核黄素-紫外线A巩膜胶原交联治疗病理性近视的主要因素

明春秀1,刘丽梅2,张少斌2   

  1. 1 滨州医学院,山东烟台 264003; 2 潍坊眼科医院,山东 261000
  • 收稿日期:2019-01-06 出版日期:2019-06-22 发布日期:2019-06-25
  • 通讯作者: 张少斌,Email:zhangsb518@163.com

Main factors affecting riboflavin-UVA scleral collagen cross-linking for pathological myopia Ming

Ming Chunxiu1, Liu Limei2, Zhang Shaobin2   

  1. 1 Binzhou Medical University, Yantai Shandong 264003, China; 2 Weifang Eye Hospital, Weifang Shandong 261000, China
  • Received:2019-01-06 Online:2019-06-22 Published:2019-06-25
  • Contact: Zhang Shaobin, Email: zhangsb518@163. com

摘要:

核黄素-紫外线A巩膜胶原交联术可增强胶原纤维机械强度,能延缓动物眼眼轴的增长,从而阻止病理性近视的进展。影响核黄素-紫外线A巩膜胶原交联效果的主要因素有紫外线、核黄素、巩膜等,紫外线照射过多可造成视网膜等眼内结构的损伤,核黄素浓度过大可减弱紫外线对巩膜的交联作用,巩膜过薄不能阻断过多的紫外线对眼内结构的损伤。(国际眼科纵览,2019, 43:180-183)

Abstract:

Riboflavin-ultraviolet A scleral collagen cross-linking can enhance the strength of collagen fibers, delay the growth of animal eye axial length, and thus prevent the progress of pathological myopia. The main factors affecting the effect of riboflavin-ultraviolet A scleral collagen cross-linking are ultraviolet, riboflavin and sclera. Excessive ultraviolet can damage retina and other intraocular structures. Excessive riboflavin concentration can weaken the cross-linking. A thin sclera can not block the damage of ultraviolet radiation on intraocular structures. (Int Rev Ophthalmol, 2019, 43: 180-183)